BDBM50117599 1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl)-1-hydroxy-3-oxo-propyl]-1-methyl-piperidinium; bromide::CHEMBL315013

SMILES COc1cc2cc(sc2cc1OC)C(=O)CC(O)C1CC[N+](C)(Cc2ccccc2)CC1

InChI Key InChIKey=VTAYNRZFMWKVMV-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50117599   

TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117599(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  219nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117599(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  219nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117599(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataEC50:  170nMAssay Description:In vitro reversal of vecuronium-induced block in isolated guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117599(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  665nMAssay Description:In vitro reversal of vecuronium-induced block in isolated guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117599(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  43nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed