BDBM50117646 CHEMBL3613628

SMILES CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)C(C)(C)C)cc1

InChI Key InChIKey=PYHXVRKSQDWXQT-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117646   

TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis

Curated by ChEMBL

LigandBDBM50117646(CHEMBL3613628)Copy SMILESCopy InChI

Affinity DataIC50:  390nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis

Curated by ChEMBL

LigandBDBM50117646(CHEMBL3613628)Copy SMILESCopy InChI

Affinity DataIC50:  1.05E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI