BDBM50117648 CHEMBL3613626

SMILES CC(C)N1CCN(CC1)S(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)-c2ccccn2)cc1

InChI Key InChIKey=HRZAGAILOLRXSQ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117648   

TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Renovis

Curated by ChEMBL

LigandBDBM50117648(CHEMBL3613626)Copy SMILESCopy InChI

Affinity DataIC50:  4.93E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Renovis

Curated by ChEMBL

LigandBDBM50117648(CHEMBL3613626)Copy SMILESCopy InChI

Affinity DataIC50:  6.49E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI