BDBM50117936 (+)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetrahydropyrido[2',3':4,5]cyclohepta[e]indol-12-yl]hexahydro-1-pyridinyl}-2-oxoethyl)-1-pyridiniumolate::(-)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetrahydropyrido[2',3':4,5]cyclohepta[e]indol-12-yl]hexahydro-1-pyridinyl}-2-oxoethyl)-1-pyridiniumolate::CHEMBL339026

SMILES CCCc1c[nH]c2c(Cl)cc3CCc4cccnc4[C@H](C4CCN(CC4)C(=O)Cc4cc[n+]([O-])cc4)c3c12

InChI Key InChIKey=NCXYOUKRMKDMLX-MUUNZHRXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117936   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117936((+)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetra...)
Affinity DataIC50:  65nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50117936((+)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetra...)
Affinity DataIC50: >190nMAssay Description:Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-valMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed