BDBM50118289 7-Naphthalen-2-yl-8,9-dihydro-7H-7a,10-diaza-pentaleno[1,2-a]naphthalen-7-ol::CHEMBL340281
SMILES OC1(N2CCN=C2c2c1ccc1ccccc21)c1ccc2ccccc2c1
InChI Key InChIKey=AYESQVUVFADUMC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50118289
Affinity DataKi: 2.83nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrin transpoter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program/Nih
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program/Nih
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program/Nih
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program/Nih
Curated by ChEMBL
Affinity DataIC50: 38.1nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair