BDBM50118293 7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pentaleno[1,2-a]naphthalen-7-ol::CHEMBL133646

SMILES OC1(N2CCN=C2c2c1ccc1ccccc21)c1ccc(Cl)cc1

InChI Key InChIKey=GYTGCOARTYXPAX-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50118293   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118293(7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...)
Affinity DataKi:  27.2nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118293(7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...)
Affinity DataKi:  33.4nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrin transpoter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118293(7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...)
Affinity DataKi:  224nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program/Nih

Curated by ChEMBL
LigandPNGBDBM50118293(7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...)
Affinity DataIC50:  16nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118293(7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...)
Affinity DataIC50:  10.6nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program/Nih

Curated by ChEMBL
LigandPNGBDBM50118293(7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...)
Affinity DataIC50:  16.0nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed