BDBM50118294 7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaza-benzo[c]fluoren-7-ol::CHEMBL334577

SMILES OC1(N2CCCN=C2c2c1ccc1ccccc21)c1ccc(Cl)cc1

InChI Key InChIKey=ADCPRYKGPAHETD-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50118294   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)
Affinity DataKi:  2.01nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrin transpoter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)
Affinity DataKi:  5.5nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)
Affinity DataIC50:  37.3nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)
Affinity DataIC50:  2.10nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)
Affinity DataIC50:  37nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed