BDBM50118294 7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaza-benzo[c]fluoren-7-ol::CHEMBL334577
SMILES OC1(N2CCCN=C2c2c1ccc1ccccc21)c1ccc(Cl)cc1
InChI Key InChIKey=ADCPRYKGPAHETD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50118294
Affinity DataKi: 2.01nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrin transpoter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 37.3nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University
Curated by ChEMBL
Drew University
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair