BDBM50118295 11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-benzo[4,5]imidazo[2,1-a]isoindol-11-ol::CHEMBL337020

SMILES OC1(N2[C@H]3CCCC[C@@H]3N=C2c2ccccc12)c1ccc(Cl)cc1

InChI Key InChIKey=KLRMDPMJYLBCKY-IJXZTRCJSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50118295   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118295(11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-b...)
Affinity DataKi:  152nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118295(11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-b...)
Affinity DataKi:  600nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118295(11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-b...)
Affinity DataKi:  690nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrin transpoter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118295(11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-b...)
Affinity DataIC50:  2.70nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118295(11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-b...)
Affinity DataIC50:  34.2nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed