BDBM50118479 2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyric acid::CHEMBL334842

SMILES N[C@H](CCc1ns[nH]c1=O)C(O)=O

InChI Key InChIKey=AJASJCCJLLTPOF-GSVOUGTGSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50118479   

TargetMetabotropic glutamate receptor 1(RAT)
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118479(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118479(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118479(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50:  3.70E+4nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118479(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lifeguard 1(Rattus norvegicus)
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118479(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataIC50:  2.87E+5nMAssay Description:Binding affinity towards N-methyl-D-aspartate glutamate receptor (NMDA) determined electrophysically using the rat cortical wedge model.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed