BDBM50118551 CHEMBL137392::Sulfamic acid 2-tert-butyl-4-oxo-4H-chromen-6-yl ester

SMILES CC(C)(C)c1cc(=O)c2cc(OS(N)(=O)=O)ccc2o1

InChI Key InChIKey=PGFMBHKYSULPEO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118551   

TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50118551(CHEMBL137392 | Sulfamic acid 2-tert-butyl-4-oxo-4H...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against purified human steroid sulfatase (STS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50118551(CHEMBL137392 | Sulfamic acid 2-tert-butyl-4-oxo-4H...)
Affinity DataIC50:  0.0470nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50118551(CHEMBL137392 | Sulfamic acid 2-tert-butyl-4-oxo-4H...)
Affinity DataIC50:  22nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed