BDBM50119524 4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5-yl)pyridine::4-[5-(4-Fluoro-phenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridine::CHEMBL113419::ML-3375
SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1
InChI Key InChIKey=IKQIPPKRAFLUKQ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50119524
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University TüBingen
Curated by ChEMBL
Eberhard-Karls-University TüBingen
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 (P38 MAPK)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of p38-related TNF-alpha release by whole blood cells at 10 e-4 to 10 e-8 MMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against TNF-alpha release in PBM cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 at 10 e-4 to 10 e-8 M concentrationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of p38-related IL1-beta release by whole blood cells at 10 e-4 to 10 e-8 MMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against induction of IL-1-beta release in PBMCsMore data for this Ligand-Target Pair