BDBM50120986 CHEMBL326331::[(S)-1-((4R,6R,6aS)-6-Ethyl-4-methanesulfonyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl)-2-methyl-propyl]-carbamic acid tert-butyl ester

SMILES CC[C@@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)N(C1=O)S(C)(=O)=O

InChI Key InChIKey=RVRXGFXYFFQPPA-CBBWQLFWSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120986   

TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986(CHEMBL326331 | [(S)-1-((4R,6R,6aS)-6-Ethyl-4-metha...)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986(CHEMBL326331 | [(S)-1-((4R,6R,6aS)-6-Ethyl-4-metha...)
Affinity DataIC50:  1.93E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986(CHEMBL326331 | [(S)-1-((4R,6R,6aS)-6-Ethyl-4-metha...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986(CHEMBL326331 | [(S)-1-((4R,6R,6aS)-6-Ethyl-4-metha...)
Affinity DataIC50:  1.94E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed