BDBM50123026 CHEMBL3623232

SMILES NS(=O)(=O)Oc1ccc(CN(c2ccc(cc2)C#N)n2ccnc2)c(F)c1

InChI Key InChIKey=JQBLWLMMDJRXNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123026   

TargetAromatase(Homo sapiens (Human))
American University Of Ras Al Khaimah

Curated by ChEMBL
LigandPNGBDBM50123026(CHEMBL3623232)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione as substrate after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
American University Of Ras Al Khaimah

Curated by ChEMBL
LigandPNGBDBM50123026(CHEMBL3623232)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of aromatase in human JEG3 cells using [1beta-3H] androstenedione as substrate assessed as tritiated H2O release after 1 hr by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
American University Of Ras Al Khaimah

Curated by ChEMBL
LigandPNGBDBM50123026(CHEMBL3623232)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S as substrate after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed