BDBM50123310 1,3-Diethyl-5-(1-methyl-1H-indol-3-ylmethylene)-2-thioxo-dihydro-pyrimidine-4,6-dione::CHEMBL359346

SMILES [#6]-[#6]-[#7]-1-[#6](=S)-[#7](-[#6]-[#6])-[#6](=O)\[#6](=[#6]\c2cn(-[#6])c3ccccc23)-[#6]-1=O

InChI Key InChIKey=MZHYJFROIIBVCC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123310   

TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123310(1,3-Diethyl-5-(1-methyl-1H-indol-3-ylmethylene)-2-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of TNF-alpha binding to TNFRc1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed