BDBM50124518 (E)-3-(3'-Adamantan-1-yl-4'-hydroxy-biphenyl-4-yl)-acrylic acid::(E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]cinnamic acid::CHEMBL442016

SMILES OC(=O)\C=C\c1ccc(cc1)-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=QAWBIEIZDDIEMW-FPYGCLRLSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124518   

TargetPup--protein ligase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50124518((E)-3-(3'-Adamantan-1-yl-4'-hydroxy-biphenyl-4-yl)...)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PafA expressed in Escherichia coli BL-21(DE3) assessed as inhibition of pup-ylation using Mtb PanB substrate...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50124518((E)-3-(3'-Adamantan-1-yl-4'-hydroxy-biphenyl-4-yl)...)
Affinity DataEC50:  200nMAssay Description:Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed