BDBM50125049 CHEMBL3623830
SMILES CCC(=O)N[C@@H]1CCCc2c1cncc2-c1ccc(cc1)C#N
InChI Key InChIKey=ITXORCJLPUUDIY-GOSISDBHSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50125049
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of mouse CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Roche Pharma Research And Early Development (Pred)
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair