BDBM50126777 CHEMBL33835::Cyano-[5-fluoro-1-(4-fluoro-benzyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-acetic acid

SMILES OC(=O)C(C#N)C1C(=O)N(Cc2ccc(F)cc2)c2ccc(F)cc12

InChI Key InChIKey=IPSRZDHLMFNRDU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126777   

TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50126777(CHEMBL33835 | Cyano-[5-fluoro-1-(4-fluoro-benzyl)-...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50126777(CHEMBL33835 | Cyano-[5-fluoro-1-(4-fluoro-benzyl)-...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50126777(CHEMBL33835 | Cyano-[5-fluoro-1-(4-fluoro-benzyl)-...)
Affinity DataIC50:  490nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed