BDBM50128065 CHEMBL304858::CHEMBL324162::N-allyl-6-(4-(4-bromobenzoyl)-3-fluorophenoxy)-N-methylhexan-1-aminium::[4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONE::{4-[6-(Allyl-methyl-amino)-hexyloxy]-2-fluoro-phenyl}-(4-bromo-phenyl)-methanone
SMILES CN(CCCCCCOc1ccc(C(=O)c2ccc(Br)cc2)c(F)c1)CC=C
InChI Key InChIKey=CMYCCJYVZIMDFU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50128065
TargetSqualene--hopene cyclase(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldariusMore data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human C-terminal His6-tagged OSC expressed in Pichia pastoris GS115 using 2,3-oxidosqualene as substrate after 90 mins by 1H NMR methodMore data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human liver microsome 2,3-OSC after 1 hr by Silica gel plate phosphor imagingMore data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 224nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair