BDBM50128080 CHEMBL217379::DYNORPHIN(1-8)-OH::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=WRPLGMBDXVBPEG-VGXZEHLRSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50128080   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50128080(CHEMBL217379 | DYNORPHIN(1-8)-OH | Tyr-Gly-Gly-Phe...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50128080(CHEMBL217379 | DYNORPHIN(1-8)-OH | Tyr-Gly-Gly-Phe...)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50128080(CHEMBL217379 | DYNORPHIN(1-8)-OH | Tyr-Gly-Gly-Phe...)
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50128080(CHEMBL217379 | DYNORPHIN(1-8)-OH | Tyr-Gly-Gly-Phe...)
Affinity DataKi:  3.60nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50128080(CHEMBL217379 | DYNORPHIN(1-8)-OH | Tyr-Gly-Gly-Phe...)
In DepthDetails PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50128080(CHEMBL217379 | DYNORPHIN(1-8)-OH | Tyr-Gly-Gly-Phe...)
Affinity DataKi:  4.60nMAssay Description:In vitro binding affinity towards human Opioid receptor kappa 1 on CHO cell membranes using [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50128080(CHEMBL217379 | DYNORPHIN(1-8)-OH | Tyr-Gly-Gly-Phe...)
Affinity DataKi:  8.5nMAssay Description:In vitro binding affinity to human Opioid receptor delta 1 on CHO cell membranes using [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50128080(CHEMBL217379 | DYNORPHIN(1-8)-OH | Tyr-Gly-Gly-Phe...)
Affinity DataKi:  35nMAssay Description:In vitro binding affinity to human Opioid receptor mu 1 on CHO cell membranes using [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed