BDBM50128370 (S)-1-(4-(4-methoxybenzo[b]thiophen-2-yl)piperidin-1-yl)-3-(2-methyl-1H-indol-4-yloxy)propan-2-ol::(S)-1-[4-(4-Methoxy-benzo[b]thiophen-2-yl)-piperidin-1-yl]-3-(2-methyl-1H-indol-4-yloxy)-propan-2-ol::CHEMBL300340

SMILES COc1cccc2sc(cc12)C1CCN(C[C@H](O)COc2cccc3[nH]c(C)cc23)CC1

InChI Key InChIKey=SYWVBRYJGFTBHV-IBGZPJMESA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128370   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128370((S)-1-(4-(4-methoxybenzo[b]thiophen-2-yl)piperidin...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity was determined towards 5-hydroxytryptamine 1A receptor receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128370((S)-1-(4-(4-methoxybenzo[b]thiophen-2-yl)piperidin...)
Affinity DataKi:  4.83nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128370((S)-1-(4-(4-methoxybenzo[b]thiophen-2-yl)piperidin...)
Affinity DataKi:  51nMAssay Description:Binding affinity towards serotonin [5-HT] reuptake site labeled with [3H]-paroxetine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128370((S)-1-(4-(4-methoxybenzo[b]thiophen-2-yl)piperidin...)
Affinity DataKi:  51.2nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed