BDBM50129730 7-[3,5-Bis-(1,1-dimethyl-propyl)-2-methoxy-phenyl]-3-methyl-octa-2,4,6-trienoic acid::CHEMBL91185

SMILES CCC(C)(C)c1cc(\C(C)=C/C=C/C(/C)=C/C(O)=O)c(OC)c(c1)C(C)(C)CC

InChI Key InChIKey=DTZUKXVGXVOCKJ-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50129730   

TargetRetinoic acid receptor RXR-alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129730(7-[3,5-Bis-(1,1-dimethyl-propyl)-2-methoxy-phenyl]...)
Affinity DataEC50:  506nMAssay Description:Inhibition of Retinoic acid receptor RXR-alpha agonist activity in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50129730(7-[3,5-Bis-(1,1-dimethyl-propyl)-2-methoxy-phenyl]...)
Affinity DataEC50:  6nMAssay Description:Transcriptional activity against RXR:PPAR-gamma synergy was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129730(7-[3,5-Bis-(1,1-dimethyl-propyl)-2-methoxy-phenyl]...)
Affinity DataKi:  2nMAssay Description:Binding affinity against Retinoic acid receptor RXR-alpha was determined in vitro by using [3H]9-cis-RA as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129730(7-[3,5-Bis-(1,1-dimethyl-propyl)-2-methoxy-phenyl]...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity against Retinoic acid receptor gamma was determined in vitro by using [3H]ATRA as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed