BDBM50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole

SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl

InChI Key InChIKey=CEUORZQYGODEFX-UHFFFAOYSA-N

Data  273 KI  38 IC50  35 EC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130293   

TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  0.687nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by MicroBeta scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(3) dopamine receptor(Homo sapiens)
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by MicroBeta scintillation cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed