BDBM50130443 4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-benzamide::CHEMBL103479

SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)nc12

InChI Key InChIKey=RUJUSCZEDDAGAW-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50130443   

Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  7.60nMAssay Description:In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  7.60nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  56nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  660nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1E recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  730nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  1.20E+3nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1B recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  1.90E+3nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 2C recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  4.00E+3nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi:  4.80E+3nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 2A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi: >5.00E+3nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130443(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 2B recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed