BDBM50131382 (2R,3R,4R,5S)-1-(4-Cyclohexyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL327578

SMILES ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1S(=O)(=O)c1ccc(OC2CCCCC2)cc1

InChI Key InChIKey=KFASYAQTQCGPKV-YLFCFFPRSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50131382   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL
LigandPNGBDBM50131382((2R,3R,4R,5S)-1-(4-Cyclohexyloxy-benzenesulfonyl)-...)
Affinity DataKi:  0.930nMAssay Description:Inhibition of recombinant human matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL
LigandPNGBDBM50131382((2R,3R,4R,5S)-1-(4-Cyclohexyloxy-benzenesulfonyl)-...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of recombinant human matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL
LigandPNGBDBM50131382((2R,3R,4R,5S)-1-(4-Cyclohexyloxy-benzenesulfonyl)-...)
Affinity DataKi:  67nMAssay Description:Inhibition of recombinant human TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Hokkaido Collaboration Center

Curated by ChEMBL
LigandPNGBDBM50131382((2R,3R,4R,5S)-1-(4-Cyclohexyloxy-benzenesulfonyl)-...)
Affinity DataKi:  100nMAssay Description:Inhibition of recombinant human matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed