BDBM50131587 CHEMBL324048::{2-Chloro-4-[5-chloro-3-(4-methanesulfonyl-phenyl)-3H-imidazol-4-yl]-phenyl}-dimethyl-amine

SMILES CN(C)c1ccc(cc1Cl)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=HOMYPBUWCGCCFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131587   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131587(CHEMBL324048 | {2-Chloro-4-[5-chloro-3-(4-methanes...)
Affinity DataIC50:  27nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131587(CHEMBL324048 | {2-Chloro-4-[5-chloro-3-(4-methanes...)
Affinity DataIC50:  1.90E+3nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed