BDBM50131592 4-Bromo-5-(4-fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole::CHEMBL326577

SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Br)c1-c1ccc(F)cc1

InChI Key InChIKey=ZFPOIPOXORZJQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131592   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131592(4-Bromo-5-(4-fluoro-phenyl)-1-(4-methanesulfonyl-p...)
Affinity DataIC50:  36nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131592(4-Bromo-5-(4-fluoro-phenyl)-1-(4-methanesulfonyl-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed