BDBM50131803 CHEMBL3634129
SMILES C[C@@]1(N=C(N)CO[C@@H]1C(F)(F)F)c1cc(NC(=O)c2cnc(Cl)cn2)ccc1F
InChI Key InChIKey=RCCXUFNTTANXEO-JKSUJKDBSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50131803
Affinity DataIC50: 14nMAssay Description:Inhibition of BACE1 in human SKNBE2 cells expressing wild type human APP695 assessed as reduction in amyloid beta-42 production after 18 hrs by sandw...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of BACE1 (unknown origin) using APP Swedish mutant harboring Lys-Met/Asn-Leu mutation in beta-secretase cleavage site as substrate by FRET...More data for this Ligand-Target Pair