BDBM50132449 3-((1-(4-morpholino-4-oxobutyl)-1H-indol-3-yl)methylene)-2-oxoindoline-5-sulfonamide::3-[1-[1-(4-Morpholin-4-yl-4-oxo-butyl)-1H-indol-3-yl]-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide::CHEMBL322152
SMILES NS(=O)(=O)c1ccc2NC(=O)\C(=C/c3cn(CCCC(=O)N4CCOCC4)c4ccccc34)c2c1
InChI Key InChIKey=JKADGPOGQFJHIW-STZFKDTASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50132449
Affinity DataIC50: 133nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 5.60E+3nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 133nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair