BDBM50133114 5-{2-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]-cyclopent-1-enyl}-3-methyl-penta-2,4-dienoic acid::CHEMBL336086

SMILES CC(C)c1cc(C(C)C)c(OCCCF)c(c1)C1=C(CCC1)\C=C\C(\C)=C\C(O)=O

InChI Key InChIKey=HCXVTFDYDVOCPY-XJZNFUNPSA-N

Data  8 KI  1 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50133114   

TargetRetinoic acid receptor RXR-alpha(RAT)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133114(5-{2-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...)
Show SMILES CC(C)c1cc(C(C)C)c(OCCCF)c(c1)C1=C(CCC1)\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C26H35FO3/c1-17(2)21-15-23(18(3)4)26(30-13-7-12-27)24(16-21)22-9-6-8-20(22)11-10-19(5)14-25(28)29/h10-11,14-18H,6-9,12-13H2,1-5H3,(H,28,29)/b11-10+,19-14+
Affinity DataKi:  1.90nMAssay Description:Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-beta(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133114(5-{2-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...)
Show SMILES CC(C)c1cc(C(C)C)c(OCCCF)c(c1)C1=C(CCC1)\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C26H35FO3/c1-17(2)21-15-23(18(3)4)26(30-13-7-12-27)24(16-21)22-9-6-8-20(22)11-10-19(5)14-25(28)29/h10-11,14-18H,6-9,12-13H2,1-5H3,(H,28,29)/b11-10+,19-14+
Affinity DataKi:  5.70nMAssay Description:Binding affinity for Retinoic acid receptor RXR-beta was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-gamma(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133114(5-{2-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...)
Show SMILES CC(C)c1cc(C(C)C)c(OCCCF)c(c1)C1=C(CCC1)\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C26H35FO3/c1-17(2)21-15-23(18(3)4)26(30-13-7-12-27)24(16-21)22-9-6-8-20(22)11-10-19(5)14-25(28)29/h10-11,14-18H,6-9,12-13H2,1-5H3,(H,28,29)/b11-10+,19-14+
Affinity DataKi:  7.60nMAssay Description:Binding affinity for Retinoic acid receptor RXR-gamma was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair
TargetRetinoic acid receptor, gamma(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133114(5-{2-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...)
Show SMILES CC(C)c1cc(C(C)C)c(OCCCF)c(c1)C1=C(CCC1)\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C26H35FO3/c1-17(2)21-15-23(18(3)4)26(30-13-7-12-27)24(16-21)22-9-6-8-20(22)11-10-19(5)14-25(28)29/h10-11,14-18H,6-9,12-13H2,1-5H3,(H,28,29)/b11-10+,19-14+
Affinity DataKi:  2.22E+3nMAssay Description:Binding affinity for Retinoic acid receptor gamma was determined by competing with 3[H]-ATRAMore data for this Ligand-Target Pair
TargetRetinoic acid receptor, alpha, isoform CRA_b(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133114(5-{2-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...)
Show SMILES CC(C)c1cc(C(C)C)c(OCCCF)c(c1)C1=C(CCC1)\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C26H35FO3/c1-17(2)21-15-23(18(3)4)26(30-13-7-12-27)24(16-21)22-9-6-8-20(22)11-10-19(5)14-25(28)29/h10-11,14-18H,6-9,12-13H2,1-5H3,(H,28,29)/b11-10+,19-14+
Affinity DataKi:  2.48E+3nMAssay Description:Binding affinity for Retinoic acid receptor alpha was determined by competing with 3[H]-ATRAMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133114(5-{2-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...)
Show SMILES CC(C)c1cc(C(C)C)c(OCCCF)c(c1)C1=C(CCC1)\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C26H35FO3/c1-17(2)21-15-23(18(3)4)26(30-13-7-12-27)24(16-21)22-9-6-8-20(22)11-10-19(5)14-25(28)29/h10-11,14-18H,6-9,12-13H2,1-5H3,(H,28,29)/b11-10+,19-14+
Affinity DataKi:  4.71E+3nMAssay Description:Binding affinity for Peroxisome proliferator activated receptor gamma was determinedMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133114(5-{2-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...)
Show SMILES CC(C)c1cc(C(C)C)c(OCCCF)c(c1)C1=C(CCC1)\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C26H35FO3/c1-17(2)21-15-23(18(3)4)26(30-13-7-12-27)24(16-21)22-9-6-8-20(22)11-10-19(5)14-25(28)29/h10-11,14-18H,6-9,12-13H2,1-5H3,(H,28,29)/b11-10+,19-14+
Affinity DataKi:  8.27E+3nMAssay Description:Binding affinity for Retinoic acid receptor beta was determined by competing with 3[H]-ATRAMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Rattus norvegicus)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133114(5-{2-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...)
Show SMILES CC(C)c1cc(C(C)C)c(OCCCF)c(c1)C1=C(CCC1)\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C26H35FO3/c1-17(2)21-15-23(18(3)4)26(30-13-7-12-27)24(16-21)22-9-6-8-20(22)11-10-19(5)14-25(28)29/h10-11,14-18H,6-9,12-13H2,1-5H3,(H,28,29)/b11-10+,19-14+
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for peroxisome Peroxisome proliferator activated receptor alpha was determinedMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(RAT)
Ligand Pharmaceuticals Inc

Curated by ChEMBL
LigandPNGBDBM50133114(5-{2-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phenyl]...)
Show SMILES CC(C)c1cc(C(C)C)c(OCCCF)c(c1)C1=C(CCC1)\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C26H35FO3/c1-17(2)21-15-23(18(3)4)26(30-13-7-12-27)24(16-21)22-9-6-8-20(22)11-10-19(5)14-25(28)29/h10-11,14-18H,6-9,12-13H2,1-5H3,(H,28,29)/b11-10+,19-14+
Affinity DataIC50: 3.30nMAssay Description:Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RAMore data for this Ligand-Target Pair