BDBM50133365 CHEMBL138593::N-[2-Furan-2-yl-8-(3-phenyl-propyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-2-phenoxy-acetamide

SMILES O=C(COc1ccccc1)Nc1nc2nn(CCCc3ccccc3)cc2c2nc(nn12)-c1ccco1

InChI Key InChIKey=DSJNSMNLGNQEBL-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50133365   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133365(CHEMBL138593 | N-[2-Furan-2-yl-8-(3-phenyl-propyl)...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A2B receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50133365(CHEMBL138593 | N-[2-Furan-2-yl-8-(3-phenyl-propyl)...)
Affinity DataKi:  40nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50133365(CHEMBL138593 | N-[2-Furan-2-yl-8-(3-phenyl-propyl)...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-MRE3008-F20 from human A3 receptors expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133365(CHEMBL138593 | N-[2-Furan-2-yl-8-(3-phenyl-propyl)...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]-ZM-241,385 from human adenosine A2A receptors expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133365(CHEMBL138593 | N-[2-Furan-2-yl-8-(3-phenyl-propyl)...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133365(CHEMBL138593 | N-[2-Furan-2-yl-8-(3-phenyl-propyl)...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against NECA stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed