BDBM50133435 4-(2-Chloro-phenyl)-1-ethyl-6-methyl-1,4-dihydro-pyridine-2,3,5-tricarboxylic acid 5-isopropyl ester::CHEMBL114950

SMILES CCN1C(C)=C(C(C(C(O)=O)=C1C(O)=O)c1ccccc1Cl)C(=O)OC(C)C

InChI Key InChIKey=OIDMNXKQVHXWLV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50133435   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133435(4-(2-Chloro-phenyl)-1-ethyl-6-methyl-1,4-dihydro-p...)
Affinity DataIC50:  39nMAssay Description:In vitro inhibitory activity against human liver glycogen phosphorylase a (HLGPa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Universit£

Curated by ChEMBL
LigandPNGBDBM50133435(4-(2-Chloro-phenyl)-1-ethyl-6-methyl-1,4-dihydro-p...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity to rabbit muscular GPb by NMR binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133435(4-(2-Chloro-phenyl)-1-ethyl-6-methyl-1,4-dihydro-p...)
Affinity DataIC50:  138nMAssay Description:In vitro inhibitory activity against human muscle glycogen phosphorylase a (HMGPa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed