BDBM50134488 (R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-4-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL333283
SMILES Clc1ccc(C[C@@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCN(CC2)c2ccccc2Cn2cnnc2)cc1
InChI Key InChIKey=SQUPSEKHAYZJTP-FQLXRVMXSA-N
Data 6 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50134488
Affinity DataEC50: >3.00E+3nMAssay Description:In vitro cAMP accumulation in HEK cells transfected with human Melanocortin 3 receptor (hMC3R)More data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 4 receptor (mMC4R)More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Agonistic activity measured as inhibition of cAMP accumulation in HEK cells expressing human Melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:In vitro cAMP accumulation in HEK cells transfected with human Melanocortin 5 receptor (hMC5R)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro cAMP accumulation in Y1 cells transfected with mouse Melanocortin 2 receptor (mMC2R)More data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataEC50: >3.00E+3nMAssay Description:In vitro cAMP accumulation in HEK cells transfected with human Melanocortin 1 receptor (hMC1R)More data for this Ligand-Target Pair