BDBM50135532 3-{2-cyano-2-[1-(3-methyloxycarbonylanilino)-2-(3-methylphenyl)-(1S)-ethylcarboxamido]ethoxymethyl}benzoic acid::CHEMBL336115

SMILES COC(=O)c1cccc(N[C@@H](Cc2cccc(C)c2)C(=O)N[C@@H](COCc2cccc(c2)C(O)=O)C#N)c1

InChI Key InChIKey=YKGCZJXHFVVNSC-FTJBHMTQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135532   

TargetCathepsin S(Homo sapiens (Human))
Novartis Institute Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135532(3-{2-cyano-2-[1-(3-methyloxycarbonylanilino)-2-(3-...)
Affinity DataIC50:  710nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135532(3-{2-cyano-2-[1-(3-methyloxycarbonylanilino)-2-(3-...)
Affinity DataIC50:  8.60nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135532(3-{2-cyano-2-[1-(3-methyloxycarbonylanilino)-2-(3-...)
Affinity DataIC50:  210nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed