BDBM50135544 2-Chloro-5-[(R)-2-cyano-2-((S)-2-phenylamino-3-m-tolyl-propionylamino)-ethoxymethyl]-benzoic acid::CHEMBL334879

SMILES Cc1cccc(C[C@H](Nc2ccccc2)C(=O)N[C@@H](COCc2ccc(Cl)c(c2)C(O)=O)C#N)c1

InChI Key InChIKey=IHOKXHNBNUTHMF-RDGATRHJSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135544   

TargetCathepsin S(Homo sapiens (Human))
Novartis Institute Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135544(2-Chloro-5-[(R)-2-cyano-2-((S)-2-phenylamino-3-m-t...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibtitory activity against cathepsin S (catS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Novartis Institute Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135544(2-Chloro-5-[(R)-2-cyano-2-((S)-2-phenylamino-3-m-t...)
Affinity DataIC50:  8.70nMAssay Description:Inhibtitory activity against cathepsin B (catB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institute Of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50135544(2-Chloro-5-[(R)-2-cyano-2-((S)-2-phenylamino-3-m-t...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibtitory activity against cathepsin L (catL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed