BDBM50137277 2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide::CHEMBL148406

SMILES Nc1ccc(cc1)S(=O)(=O)N1CCc2cc(O)ccc2C1C(=O)NO

InChI Key InChIKey=VVZFBVIPGIVQRI-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50137277   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)
Affinity DataIC50:  835nMAssay Description:Inhibition of matrix metalloproteinase-14 (MMP-14)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)
Affinity DataIC50:  248nMAssay Description:Inhibition of matrix metalloproteinase-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of matrix metalloproteinase-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)
Affinity DataIC50:  385nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)
Affinity DataIC50:  492nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)
Affinity DataIC50:  191nMAssay Description:Inhibition of matrix metalloproteinase-12 (MMP-12)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)
Affinity DataIC50:  150nMAssay Description:Inhibition of matrix metalloproteinase-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)
Affinity DataIC50:  202nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed