BDBM50137394 ((R)-2-(3H-Indol-3-yl)-1-{3-phenyl-1-[(4-piperidin-1-yl-phenylamino)-methyl]-propylcarbamoyl}-ethyl)-carbamic acid benzyl ester::CHEMBL354132

SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCc1ccccc1)CNc1ccc(cc1)N1CCCCC1)OCc1ccccc1

InChI Key InChIKey=AEHSEGWZGNSNCT-HCJVMEMPSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50137394   

TargetProcathepsin L(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50137394(((R)-2-(3H-Indol-3-yl)-1-{3-phenyl-1-[(4-piperidin...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against recombinant human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50137394(((R)-2-(3H-Indol-3-yl)-1-{3-phenyl-1-[(4-piperidin...)
Affinity DataKi:  48nMAssay Description:Inhibitory activity against recombinant human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50137394(((R)-2-(3H-Indol-3-yl)-1-{3-phenyl-1-[(4-piperidin...)
Affinity DataKi:  3.36E+3nMAssay Description:Inhibitory activity against recombinant human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed