BDBM50138513 1-Benzyl-1-ethyl-3-(7-hydroxy-naphthalen-1-yl)-urea::CHEMBL151378

SMILES CCN(Cc1ccccc1)C(=O)Nc1cccc2ccc(O)cc12

InChI Key InChIKey=CXHBPZXJTRSPFC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138513   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50138513(1-Benzyl-1-ethyl-3-(7-hydroxy-naphthalen-1-yl)-ure...)
Affinity DataKi:  1.11E+3nMAssay Description:Binding affinity towards cloned human vanilloid receptor subtype 1 in HEK293 cell membranes using [3H]-RTX as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50138513(1-Benzyl-1-ethyl-3-(7-hydroxy-naphthalen-1-yl)-ure...)
Affinity DataIC50: >1.00E+4nMAssay Description:Increased [Ca2+] influx in HEK293 cell membranes expressing human vanilloid receptor subtype 1 (inactive)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed