BDBM50138799 CHEMBL3752513

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)OC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=JEFYLCAEXSESND-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50138799   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138799(CHEMBL3752513)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant human MMP2 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElastase(Pseudomonas aeruginosa)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138799(CHEMBL3752513)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of Bacillus thermoproteolyticus pseudolysin pretreated with compound for 15 mins followed by the addition of Abz-Ala-Gly-leu-Ala-p-nitrobe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138799(CHEMBL3752513)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant human MMP9 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138799(CHEMBL3752513)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of Bacillus thermoproteolyticus thermolysin pretreated with compound for 15 mins followed by the addition of 75 uM Abz-Ala-Gly-leu-Ala-p-n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138799(CHEMBL3752513)
Affinity DataIC50:  4.38E+5nMAssay Description:Inhibition of Bacillus thermoproteolyticus thermolysin pretreated with compound for 1 hr followed by the addition of 3.33 uM bradykinin like substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElastase(Pseudomonas aeruginosa)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138799(CHEMBL3752513)
Affinity DataIC50:  1.42E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin pretreated with compound for 1 hr followed by the addition of 1.73 uM bradykinin like substrate by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed