BDBM50138983 (S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic acid::2-(S)-Amino-5-(2-methyl-isothioureido)-pentanoic acid::2-Amino-5-(2-methyl-isothioureido)-pentanoic acid::CHEMBL106516::N~5~-[(E)-imino(methylsulfanyl)methyl]-L-ornithine::S-methyl-L-thiocitrulline::SMTC, 5

SMILES CSC(N)=NCCC[C@H](N)C(O)=O

InChI Key InChIKey=NGVMVBQRKZPFLB-YFKPBYRVSA-N

Data  1 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50138983   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
The University of Texas

LigandPNGBDBM50138983((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataKi:  50nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
The University of Texas

LigandPNGBDBM50138983((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50138983((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against human endothelial nitric oxide synthase expressed in Sf-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50138983((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataIC50:  60nMAssay Description:Inhibitory concentration against human neuronal nitric oxide synthase expressed in Sf-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM50138983((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50138983((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration against human inducible nitric oxide synthase expressed in Sf-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed