BDBM50141011 6-(3,5-Dimethoxy-benzyl)-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL38053

SMILES COc1cc(Cc2cnc3nc(N)nc(N)c3c2C)cc(OC)c1

InChI Key InChIKey=APTJXHNURWYTPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141011   

TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141011(6-(3,5-Dimethoxy-benzyl)-5-methyl-pyrido[2,3-d]pyr...)
Affinity DataIC50:  0.640nMAssay Description:Inhibitory concentration against dihydrofolate reductase of Mycobacterium aviumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141011(6-(3,5-Dimethoxy-benzyl)-5-methyl-pyrido[2,3-d]pyr...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory concentration against dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed