BDBM50143215 CHEMBL3758457

SMILES ONC(=O)\C=C\c1ccc(\C=C(\CNC2CC2)c2ccc(F)cc2)cc1

InChI Key InChIKey=NODIYCZWVUUEMT-HTZRGULJSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50143215   

TargetHistone deacetylase 6(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143215(CHEMBL3758457)
Affinity DataIC50:  27nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143215(CHEMBL3758457)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143215(CHEMBL3758457)
Affinity DataIC50:  16nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143215(CHEMBL3758457)
Affinity DataIC50:  54nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143215(CHEMBL3758457)
Affinity DataIC50:  25nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143215(CHEMBL3758457)
Affinity DataIC50:  42nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143215(CHEMBL3758457)
Affinity DataIC50:  354nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143215(CHEMBL3758457)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143215(CHEMBL3758457)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143215(CHEMBL3758457)
Affinity DataIC50:  927nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143215(CHEMBL3758457)
Affinity DataIC50:  319nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed