BDBM50143762 (2,6-Dimethyl-phenyl)-[4'-methyl-4-(4-trifluoromethyl-phenylamino)-[1,4']bipiperidinyl-1'-yl]-methanone::CHEMBL58897

SMILES Cc1cccc(C)c1C(=O)N1CCC(C)(CC1)N1CCC(CC1)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=ZWHIPXXJCJBHBG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50143762   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143762((2,6-Dimethyl-phenyl)-[4'-methyl-4-(4-trifluoromet...)
Affinity DataIC50:  27.3nMAssay Description:Rises in intracellular [Ca2+] levels by using [Ca2+] sensitive Fluo4 dye in C-C chemokine receptor type 5-transfected CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143762((2,6-Dimethyl-phenyl)-[4'-methyl-4-(4-trifluoromet...)
Affinity DataIC50:  0.800nMAssay Description:Antagonistic activity against human C-C chemokine receptor type 5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143762((2,6-Dimethyl-phenyl)-[4'-methyl-4-(4-trifluoromet...)
Affinity DataIC50:  1.10nMAssay Description:Antagonistic activity against monkey C-C chemokine receptor type 5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed