BDBM50143964 4-Chloro-N-(4-fluoro-phenyl)-N-{1-[2-hydroxy-3-(4-methoxy-phenoxy)-propyl]-piperidin-4-yl}-benzamide::CHEMBL416848

SMILES COc1ccc(OCC(O)CN2CCC(CC2)N(C(=O)c2ccc(Cl)cc2)c2ccc(F)cc2)cc1

InChI Key InChIKey=LRGXNDRYQBWFPC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143964   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50143964(4-Chloro-N-(4-fluoro-phenyl)-N-{1-[2-hydroxy-3-(4-...)
Affinity DataKi:  2.00E+3nMAssay Description:Predictive competitive inhibition of cytochrome P450 2D6 was determined in silicoMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Arqule

Curated by ChEMBL
LigandPNGBDBM50143964(4-Chloro-N-(4-fluoro-phenyl)-N-{1-[2-hydroxy-3-(4-...)
Affinity DataIC50:  214nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed