BDBM50144936 CHEMBL1090::VIDARABINE::adenine arabinoside

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O

InChI Key InChIKey=OIRDTQYFTABQOQ-UHTZMRCNSA-N

Data  1 KI  2 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50144936   

TargetAdenosylhomocysteinase(Mus musculus)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50144936(CHEMBL1090 | VIDARABINE | adenine arabinoside)
Affinity DataKi:  3.00E+4nMAssay Description:Activity determined in mouse liver S-adenosyl-L-homocysteine hydrolase and expressed as KI values.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50144936(CHEMBL1090 | VIDARABINE | adenine arabinoside)
Affinity DataIC50:  62nMAssay Description:Inhibition of human DPP4 from human Caco2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144936(CHEMBL1090 | VIDARABINE | adenine arabinoside)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition HCV NS5B-mediated RNA synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144936(CHEMBL1090 | VIDARABINE | adenine arabinoside)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition HCV RNA replicationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50144936(CHEMBL1090 | VIDARABINE | adenine arabinoside)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay