BDBM50145022 1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-propyl]-piperazine::1-cyclohexyl-4-(3-(5-methoxynaphthalen-1-yl)propyl)piperazine::CHEMBL535856::CHEMBL75286::PB-183

SMILES COc1cccc2c(CCCN3CCN(CC3)C3CCCCC3)cccc12

InChI Key InChIKey=OAXSBEWCGPXYFN-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50145022   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50145022(1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-prop...)
Affinity DataKi:  1.57nMAssay Description:In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50145022(1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-prop...)
Affinity DataKi:  1.57nMAssay Description:Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Cavia porcellus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50145022(1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-prop...)
Affinity DataKi:  4.51nMAssay Description:Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50145022(1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-prop...)
Affinity DataKi:  6.5nMAssay Description:Displacement of (+)-[3H]pentazocine from mouse sigma 1 receptor in TRAMP cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50145022(1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-prop...)
Affinity DataKi: >700nMAssay Description:In vitro binding affinity at serotonin 5-hydroxytryptamine 3 receptor in rat cortex by [3H]-granisetron displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed