BDBM50148041 CHEMBL3763444
SMILES ONC(=O)CCCCCNc1nc(Cl)nc2n(Cc3ccccc3)cnc12
InChI Key InChIKey=KXSQYCVGIABCMB-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50148041
Affinity DataIC50: 56nMAssay Description:Inhibition of C-terminal GST-tagged human recombinant HDAC2 expressed in Sf9 cells after 30 mins by microtiter plate reader analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of HDAC1/2 in human HeLa cell nuclear extract using color de Lys as substrate preincubated for 5 mins followed by substrate addition measu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of C-terminal His-tagged human recombinant HDAC8 expressed in Sf9 cells after 30 mins by microtiter plate reader analysisMore data for this Ligand-Target Pair