BDBM50148322 2-(4-Difluoromethoxy-phenyl)-2,5,6,7,8,9-hexahydro-pyrazolo[4,3-c]quinolin-3-one::CHEMBL432623

SMILES FC(F)Oc1ccc(cc1)-n1[nH]c2c3CCCCc3ncc2c1=O

InChI Key InChIKey=FTBVYUBWNUHEBT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148322   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148322(2-(4-Difluoromethoxy-phenyl)-2,5,6,7,8,9-hexahydro...)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity against gamma-aminobutyric acid A receptor, alpha 1 expressed in L(tk) cells by displacement of [3H]-Ro-15-1788More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148322(2-(4-Difluoromethoxy-phenyl)-2,5,6,7,8,9-hexahydro...)
Affinity DataKi:  2.30nMAssay Description:In vitro binding affinity against Gamma-aminobutyric acid A receptor, alpha 3 expressed in L(tk) cells by displacement of [3H]-Ro-15-1788More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed