BDBM50149384 (S)-1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL331325::Dmt-Pro-Phe-Phe-NH2
SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChI Key InChIKey=PJAMNQXPYIKTPE-KRCBVYEFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50149384
Affinity DataKi: 0.150nMAssay Description:Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Binding affinity against rat brain opioid receptor delta 1 using [3H]-DPDPE radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 99.2nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kobe Gakuin University
Curated by ChEMBL
Kobe Gakuin University
Curated by ChEMBL
Affinity DataKi: 489nMAssay Description:Displacement of [3H]U69,593 from kappa opioid receptor in Hartley guinea pig cerebellum P2 synaptosome membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair