BDBM50149940 CHEMBL3770651::US10562878, Compound 203
SMILES CN(C)CC1(CCCC(O)C1)c1ccc(Cl)c(Cl)c1
InChI Key InChIKey=BOOOMRPQCWNMRO-JOCHJYFZSA-N
Data 21 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50149940
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human 5-HT transporter expressed in HEK293 cells assessed as reduction in [3H]-5-HT reuptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human DA transporter assessed as reduction in [3H]-DA reuptakeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 2.96E+3nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
Sunovion Pharamceuticals
US Patent
Sunovion Pharamceuticals
US Patent
Affinity DataIC50: 442nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
Sunovion Pharamceuticals
US Patent
Sunovion Pharamceuticals
US Patent
Affinity DataIC50: 17nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Sunovion Pharamceuticals
US Patent
Sunovion Pharamceuticals
US Patent
Affinity DataIC50: 120nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Sunovion Pharamceuticals
US Patent
Sunovion Pharamceuticals
US Patent
Affinity DataIC50: 45nMAssay Description:Quantification of dopamine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat striatum. The uptake of...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
Sunovion Pharamceuticals
US Patent
Sunovion Pharamceuticals
US Patent
Affinity DataIC50: 747nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 426nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
Sunovion Pharamceuticals
US Patent
Sunovion Pharamceuticals
US Patent
Affinity DataIC50: 74nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
Sunovion Pharamceuticals
US Patent
Sunovion Pharamceuticals
US Patent
Affinity DataIC50: 166nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
School Of Medicine Of University Of Electronic Science And Technology Of China
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human norepinephrine transporter assessed as reduction in [3H]-NA reuptakeMore data for this Ligand-Target Pair