BDBM501505 3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3- pyridyl)-N-(1H-pyrazol-3- ylmethyl)pyrazolo[4,3-b]pyridin-7-amine, enantiomer 2::US11026923, Example 135

SMILES CCCOc1ncccc1-c1cc(NCc2cc[nH]n2)c(NC(C)CC)c(n1)C(C)=N

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 501505   

LigandPNGBDBM501505(3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3- pyridy...)
Affinity DataIC50:  1.90nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM501505(3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3- pyridy...)
Affinity DataIC50:  3.60nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM501505(3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3- pyridy...)
Affinity DataIC50:  0.0950nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent